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Hiroaki Suga Selected Research

Depsipeptides

1/2020Design, Synthesis, and Conformation-Activity Study of Unnatural Bridged Bicyclic Depsipeptides as Highly Potent Hypoxia Inducible Factor-1 Inhibitors and Antitumor Agents.

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Hiroaki Suga Research Topics

Disease

20Neoplasms (Cancer)
11/2023 - 01/2011
2Infections
01/2017 - 01/2017
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2012 - 01/2012
1Parkinson Disease (Parkinson's Disease)
01/2023
1Triple Negative Breast Neoplasms
11/2021
1Human Influenza (Influenza)
11/2021
1Pneumonia (Pneumonitis)
11/2021
1Dehydration (Water Stress)
01/2021
1Osteoporosis
12/2020
1Bone Diseases (Bone Disease)
12/2020
1Bone Resorption
12/2020
1Hypoxia (Hypoxemia)
01/2020
1Neoplasm Metastasis (Metastasis)
01/2020
1Dengue (Dengue Fever)
02/2019
1Esophageal Squamous Cell Carcinoma
01/2019
1Bile Duct Neoplasms (Bile Duct Cancer)
10/2018
1Ebola Hemorrhagic Fever
06/2017
1Obesity
03/2017
1Communicable Diseases (Infectious Diseases)
01/2017
1Carcinoma (Carcinomatosis)
01/2017
1Persistent Infection
01/2017
1Neurodegenerative Diseases (Neurodegenerative Disease)
02/2014
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
06/2012
1Type 2 Diabetes Mellitus (MODY)
01/2012
1Chronic Renal Insufficiency
01/2012

Drug/Important Bio-Agent (IBA)

11Peptides (Polypeptides)IBA
11/2023 - 01/2017
9Proteins (Proteins, Gene)FDA Link
11/2022 - 01/2006
3UbiquitinIBA
11/2023 - 01/2019
3Anti-Bacterial Agents (Antibiotics)IBA
01/2017 - 04/2013
2Proteasome Endopeptidase Complex (Proteasome)IBA
11/2023 - 04/2021
2Cyclic PeptidesIBA
11/2023 - 04/2021
2Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2023 - 01/2019
2Deubiquitinating EnzymesIBA
04/2021 - 06/2020
2EnzymesIBA
01/2021 - 01/2019
2Transfer RNA (tRNA)IBA
01/2021 - 01/2006
2LigandsIBA
01/2019 - 10/2017
2CollagenIBA
10/2018 - 01/2006
2Therapeutic UsesIBA
01/2017 - 01/2017
2Calcitriol Receptors (Calcitriol Receptor)IBA
01/2012 - 01/2011
1PolyubiquitinIBA
11/2023
1SynucleinsIBA
01/2023
1Indicators and Reagents (Reagents)IBA
01/2023
1multidrug resistance-associated protein 1IBA
01/2023
1Phosphotransferases (Kinase)IBA
11/2022
1Ubiquitin-Specific ProteasesIBA
01/2022
1Carrier Proteins (Binding Protein)IBA
11/2021
1IntegrinsIBA
11/2021
1CalciumIBA
11/2021
1Viral Envelope ProteinsIBA
11/2021
1Antiviral Agents (Antivirals)IBA
11/2021
1Oseltamivir (Tamiflu)FDA Link
11/2021
1Neuraminidase (Sialidase)IBA
11/2021
1Zanamivir (Relenza)FDA Link
11/2021
1Hemagglutinins (Hemagglutinin)IBA
11/2021
1Glu Transfer RNAIBA
01/2021
1Serine (L-Serine)FDA Link
01/2021
1Threonine (L-Threonine)FDA Link
01/2021
1AcidsIBA
01/2021
1Glutamic Acid (Glutamate)FDA Link
01/2021
1dehydrobutyrineIBA
01/2021
1dehydroalanineIBA
01/2021
1Guanosine Triphosphate (GTP)IBA
10/2020
1Guanosine Diphosphate (GDP)IBA
10/2020
1ATP dependent 26S protease (26S proteasome)IBA
06/2020
1AntibodiesIBA
01/2020
1Antineoplastic Agents (Antineoplastics)IBA
01/2020
1DepsipeptidesIBA
01/2020
1Peptide Hydrolases (Proteases)FDA Link
02/2019
1Biotin (Vitamin H)FDA Link
01/2019
1Nucleic AcidsIBA
10/2017
1Small Interfering RNA (siRNA)IBA
10/2017
1Ethylene Glycol (Monoethylene Glycol)IBA
10/2017
1Viral ProteinsIBA
06/2017
1Starch (Cornstarch)IBA
03/2017
1AmylasesFDA Link
03/2017
1Glucose (Dextrose)FDA LinkGeneric
03/2017
1OligosaccharidesIBA
03/2017
1biapenem (L 627)IBA
01/2017
1Fluorescein (Funduscein)FDA LinkGeneric
01/2017
1Histone DemethylasesIBA
01/2017
1Semaphorins (Semaphorin)IBA
11/2016
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2016
1Sirtuin 2IBA
02/2014
1CaspasesIBA
06/2012
1homoserine lactoneIBA
02/2012
1Acyl-ButyrolactonesIBA
01/2012
1Vitamin DFDA LinkGeneric
01/2012
1Parathyroid Hormone (Parathormone)IBA
01/2012
1Angiotensin Receptor AntagonistsIBA
01/2012
1calcium phosphateIBA
01/2012
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/2012
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2012
1pyrazolanthroneIBA
01/2012
125-hydroxyvitamin DIBA
01/2012
1Radiation-Sensitizing AgentsIBA
01/2012
1JNK Mitogen-Activated Protein KinasesIBA
01/2012

Therapy/Procedure

4Therapeutics
01/2022 - 10/2017
2Drug Therapy (Chemotherapy)
01/2023 - 01/2011
1Immunotherapy
01/2020
1Intravenous Administration
01/2017